By Prof. Dr. med. Heinz Grefor Wieser (auth.), B. Sutter, O. Schröttner (eds.)
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Additional info for Advances in Epilepsy Surgery and Radiosurgery
Neurology 57: 1786-1793 37. Kim JA, Chung n, Yoon PH, Kim DL Chung TS, Kim EJ, Jeong EK (2001) Transient MR signal changes in patients with generalized tonicoclonic seizure or status epilepticus: periictal diffusion-weighted imaging. AJNR 22: 1149-1160 38. Kirchberger K, Schmitt H, Hummel C, Peinemann A, Pauli E, Kettenmann B, Stefan H (1998a) Clonidine- and methohexitalinduced epileptiform discharges detected by magnetoencephalography (MEG) in patients with localization-related epilepsies. Epilepsia 39: 1104-1112 39.
Resection of cerebral tissue has the inevitable consequence that all functions subserved by that tissue are lost. Therefore removal of an epileptogenic zone that happens to lie in speach cortex or primary motor and sensory areas is not a real option for patients with medically intractable seizures. A new surgical approach referred to as multiple subpial transections 33 Surgical Treatment of Epilepsies Fig. 6. Schematic representation of multiple subpial transections. Cortical incisions are made in 5 mm-intervals (according to 14) (MST) has been developed by Morrell and colleagues in this situation (14, Fig.
Principles of Surgical Treatment Surgical interventions with a curative aim include temporal and extratemporal resections, and hemispherectomy. Recently, radiosurgery has been introduced aiming at complete seizure relief. On the other hand, callosotomy, multiple subpial transections and vagal nerve stimulation are summarized as palliative procedures aiming at significant improvement of the seizure status. According to large series, approximately 2/3 of all surgical procedures refer to the temporal lobe.
Advances in Epilepsy Surgery and Radiosurgery by Prof. Dr. med. Heinz Grefor Wieser (auth.), B. Sutter, O. Schröttner (eds.)