Download e-book for kindle: Aging of Organisms by S. Michal Jazwinski (auth.), Heinz D. Osiewacz (eds.)

By S. Michal Jazwinski (auth.), Heinz D. Osiewacz (eds.)

ISBN-10: 9048163323

ISBN-13: 9789048163328

ISBN-10: 9401706719

ISBN-13: 9789401706711

Biological getting older because the time-depending common decline of organic structures linked to a steadily expanding mortality probability is a normal phenomenom of serious value. The underlying approaches are very complicated and looking on genetic and setting elements. those elements encode or impact a community of interconnected mobile pathways. In no procedure this community has been deciphered in larger aspect. even though, the tactic of learning numerous organic platforms has permit to the identity of pathways and particular modules and makes it noticeable that getting older is the results of various overlapping mechanisms and pathways. a few of these seem to be conserved ("public") between species, others are particular or "private" and purely of value in a single or a number of organisms. This quantity within the sequence on "Biology of getting older and its modulation" particularly specializes in organismic getting older. The ebook covers examine on organisms from decrease to better complexity representing examples from very various taxa like photosynthetic vegetation, fungi, sponges, nematodes, flies, birds and mammals. this sort of huge treatise of this advanced subject presents a entire "flavor" concerning the present matters handled during this speedily transforming into clinical discipline.

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Organic getting older because the time-depending basic decline of organic platforms linked to a steadily expanding mortality probability is a common phenomenom of serious value. The underlying procedures are very advanced and counting on genetic and atmosphere elements. those components encode or have an effect on a community of interconnected mobile pathways.

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This ebook used to be conceived with the item of offering to medical professionals and scientific scholars with a possible curiosity within the disciplines of orthopaedic surgical procedure, diagnostic radiology and orthopaedic pathology, a quantity which might include easy and crucial details touching on these issues of the skeleton within which a typical curiosity exists.

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74. 75. 76. 77. 78. 79. 27 Rundlett SE, Carmen AA, Kobayashi R, Bavykin S, Turner BM, Grunstein M (1996). HDAJ and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc Nat/ Acad Sci USA 93: 14503-8. Smith JS, Brachmann CB, Pillus L, Boeke JD (1998). Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p. Genetics 149: 1205-19. Smith JS, Caputo E, Boeke JD (1999). A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors.

49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. S. MICHAL JAZWINSKI Shama S, Kirchman PA, Jiang JC, Jazwinski SM (1998). Role of RAS2 in recovery from chronic stress: effect on yeast life span. Exp Cell Res. 245: 368-78. Shama S, Lai CY, Antoniazzi JM, Jiang JC, Jazwinski SM (1998). Heat stress-induced life span extension in yeast. Exp Cell Res. 245: 379-88. Kirchman PA, Kim S, Lai CY, Jazwinski SM (1999). Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. Genetics 152: 179-90.

Nonlinearity of the aging process revealed in studies with yeast In: Bohr VA, Clark, BFC, Stevnsner T, eds. Molecular Biology of Aging. Copenhagen: Munksgaard, pp. 35--44. Jazwinski SM, Wawryn J (2001). Profiles of random change during aging contain hidden information about longevity and the aging process. J Theor Bioi. 213: 599-608. Williamson DH, Fennell DJ (1981). Non-random assortment of sister chromatids in yeast mitosis In: von Wettstein D, Stenderup A, Kielland-Brandt M, Friis J, eds. Molecular Genetics in Yeast.

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Aging of Organisms by S. Michal Jazwinski (auth.), Heinz D. Osiewacz (eds.)


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