By Richard D. Nathan
Read Online or Download Cardiac Muscle: the Regulation of Excitation and Contraction PDF
Similar nonfiction_10 books
Organic getting older because the time-depending basic decline of organic structures linked to a gradually expanding mortality hazard is a normal phenomenom of significant importance. The underlying methods are very advanced and counting on genetic and setting elements. those components encode or impact a community of interconnected mobile pathways.
This booklet used to be conceived with the item of proposing to medical professionals and clinical scholars with a possible curiosity within the disciplines of orthopaedic surgical procedure, diagnostic radiology and orthopaedic pathology, a quantity which might include simple and crucial info touching on these issues of the skeleton within which a standard curiosity exists.
- Boss Mustang: The Return of the Baddest Mustang of All Time
- Space, Time, and Archaeological Landscapes
- Vom Gesichtspunkt der Phänomenologie
- Immunobiology of the Head and Neck
Additional resources for Cardiac Muscle: the Regulation of Excitation and Contraction
M. Individual time constants are plotted for recovery from inactivation. The theoretical curves plotted in the figure were generated using Eqs. 00008 e x p ( - ( V - 5 ) / 1 7 ) . ] - 1 i0 l2 2 36 Robert S. Kass et al. A Β Fig. 5 . Calcium current (500-msec) inactivation in a calf Purkinje fiber after prepulses to positive potentials. Pulse protocol (inset): current was measured during a test pulse to 0 mV that had been preceded by 500-msec conditioning prepulses. A 10-msec return to the holding potential (—63 mV) separated prepulse from test pulse.
The relative contributions of various timedependent membrane currents to pacemaker activity in the sinoatrial node. In: "Cardiac Rate and Rhythm" (L. N. Bouman and H. J. ), pp. 5 3 - 6 8 . Martinus Nijhoff Publish ing, Boston. Brown, H. , Noble, D . , Noble, S. , and Taupignon, A. (1984a). The slow inward current, i , in the rabbit sino-atrial node investigated by voltage clamp and computer simula tion. Proc. R. Soc. London Β 222, 3 0 5 - 3 2 8 . Brown, H. , Noble, D . , Noble, S. , and Taupignon, A.
Kass et al. clamped ferret papillary muscle (Kanaya et al. 1983) and calf Purkinje fibers (Sanguinetti and Kass, 1984a). If drug-bound channels undergo voltage- and time-dependent transitions of state, the end result of a prolonged depolarization (or repeated depolarizations of sufficient duration) should be stabilization of channels in the drug-bound inactivated state. , 1984), shown below diagrammatically in a scheme first described by Hille (1977) for local anesthetic interaction with Na channels during a depolarizing event.
Cardiac Muscle: the Regulation of Excitation and Contraction by Richard D. Nathan